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Incompatibilities: As hyaluronic acid may cause a precipitation with a disinfectant tertiary ammonium such as benzalkoniurm chloride or chlorhexidine, the product should not be taken with those substances even though the active substance of Hyruan ONE is BDDE-crosslinked hyaluronate gel.
Safety and efficacy of interactions between Hyruan ONE and with other intra-articular injectables have not been established, therefore administration of Hyruan ONE with other intra-articular injectables is not recommended.
